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Genetic adjustments in OA can result in defects of a structural protein equivalent to collagen, or adjustments in the metabolism of bone and cartilage. OA is never thought of as a simple disorder following Mendelian inheritance being predominantly a multifactorial illness. Nevertheless, in the field of OA gene therapy, researches has targeted on gene switch as a supply system for therapeutic gene products, reasonably counteracting genetic abnormalities or polymorphisms. Genes, which contribute t...
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