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It appears likely that a number of factors are accountable for the observed decrements. Lack of sufficient train and improvement of muscle disuse atrophy probably contributed. Catabolic tissue processes might have been accentuated by increased cortisol secretion as a consequence of mission stress and particular person crew member response to such stress. Extra elements related to the return to Earth's gravity might even be implicated. This, the observed diminished stroke volume (cardiac output) ...